According to the UnivDatos analysis, the rising adoption of mass spectrometry for testing emerging contaminants across key sectors, increasing R&D investments in pharmaceutical and biotechnology industries, and integration of AI for enhanced data analysis and high-resolution mass spectrometry technologies drive the mass spectrometry market. As per their “Mass Spectrometry Market” report, the global market was valued at USD 6,710 million in 2024, growing at a CAGR of about 7.42% during the forecast period from 2025 - 2033 to reach USD million by 2033.

The environmental science, food safety, and pharmaceutical analysis landscape is one of continuous change, driven by the discovery of new or previously unregulated contaminants. From per- and polyfluoroalkyl substances (PFAS) to microplastics and new psychoactive substances, these "emerging contaminants" present substantial threats to human and environmental health, requiring more advanced detection and monitoring techniques. In the midst of this changing challenge, mass spectrometry (MS) has become an indispensable tool, with unmatched sensitivity, specificity, and versatility. This article discusses how the increasing use of MS for testing these new contaminants in major industries is profoundly influencing the mass spectrometry market, stimulating innovation, and redefining future trends.

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Rising Tide of Concern: Fueling the Demand for Sensitive Detection

The growing realization of new contaminants is not an abstract exercise; it directly feeds into regulatory and public pressure for safer products and environments. More stringent regulations are being enforced around the world, requiring testing for more compounds in drinking water, foodstuffs, and environmental samples. Consumer pressure, spurred by media coverage and activist groups, is also demanding transparent and honest testing. Such demand requires analysis methodologies that can find and measure such impurities to trace levels, which can be found within complex matrices. This is where mass spectrometry comes into its own.

Key Sectors Leading MS Adoption for Emerging Contaminant Testing:

The effect of emerging contaminant testing on the MS market is being experienced across several key sectors:

Environmental Monitoring: Soil, water, and air samples are regularly screened for a wide array of compounds such as PFAS, pesticides, pharmaceuticals, and microplastics. High resolution mass spectrometry (HRMS) methods, including Orbitrap and Time-of-Flight (TOF) MS, are especially useful for their capacity to detect unknown compounds and screen against hundreds of targets in parallel.

Food Safety: Concerns about food contamination with industrial chemicals, mycotoxins, and pesticides have led to regulatory measures that ensure compliance with standards of purity. Quantitative analysis using LC-MS/MS has been widely established as the means to quantify the presence of contaminants within food materials against regulatory concentrations, as well as maintaining consumer safety. The growing interest in food fraud and authenticity testing is also prompting the use of isotope ratio mass spectrometry (IRMS) for tracing the origin and content of food commodities.

Pharmaceutical Analysis: Pharmaceutical drug products are tested for impurities, degradation products, and potential contaminants. Additionally, increased use of new psychoactive substances (NPS) necessitates sophisticated analytical methods for their detection and quantification in forensic toxicology. MS-based techniques, especially LC-MS/MS and HRMS, play an imperative role in maintaining drug safety, efficacy, and surveillance for illegal drugs.

For instance, in March 2025, the University of Utah’s Department of Geology & Geophysics was awarded a million-dollar grant from the National Science Foundation (NSF) to acquire state-of-the-art mass spectrometry instrumentation for measuring isotope ratios of heavier elements at the precision needed to perform cutting-edge research into Earth’s deep past.

Market Effect: Innovation and Expansion in the MS Industry

The growing need for testing for emerging contaminants is significantly influencing the mass spectrometry market:

Technological Improvements: To meet the challenges of complex sample matrices and trace-level detection, MS manufacturers are continuously innovating. Such developments include higher sensitivity, resolution, and data handling capacity. More stable and more easy-to-use instruments, simplified methods, and better software packages for data reporting and analysis are being created.

Market Growth: Market growth is being led by the increasing demand for MS instruments, consumables, and service contracts. In addition to this, demand for specialized training and consulting services in MS-based analytical methodologies is also increasing.

For instance, in October 2024, SCIEX, a global leader in life science analytical technologies, advances its high-resolution accurate mass spectrometry portfolio with the launch of the ZenoTOF 7600+ system, accompanied by three new collaborations advancing proteomics capabilities. As the newest system in the ZenoTOF line, the ZenoTOF 7600+ system features the cutting-edge ZT Scan DIA strategy, leveraging the combination of the quadrupole dimension with the rich MS/MS data achievable from the Zeno trap. The system aims to address a research gap – simplifying the transition of protein biomarker candidates beyond the discovery stage.

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The Future of MS in Emerging Contaminant Testing

The rising adoption of mass spectrometry for testing emerging contaminants across key sectors is not just a trend, but a natural evolution prompted by increasing anxieties about human and environmental health. This demand is transforming the MS market, driving innovation, and ultimately toward a safer, more sustainable future. As new pollutants arise and analytical methods improve, mass spectrometry will certainly continue to be at the forefront of comprehending and reducing the dangers presented by these new threats.

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